The best course for kids with a fever is to let it do its own thing - that's why we have the fever.
What I normally do is wait at least 24 hrs with the child having a fever then give them minimum doses of a fever reducer as needed simply to keep them comfortable. The exception was my oldest daughter who seemed to have asthma-like symptoms triggered by a high fever.
See NPR: Pediatricians Caution Parents Against 'Fever Phobia'
Speaking of body temperature, research indicates 98.6 is ideal for preventing fungal growth [SciAm].